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Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG
P Goyal, PV Krasteva, N Van Gerven, F Gubellini, I Van den Broeck, ...
Nature 516 (7530), 250-253, 2014
3212014
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site
WY Wahlgren, E Dunevall, RA North, A Paz, M Scalise, P Bisignano, ...
Nature Communications 9 (1), 1753, 2018
812018
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
S Sainas, AC Pippione, E Lupino, M Giorgis, P Circosta, V Gaidano, ...
Journal of medicinal chemistry 61 (14), 6034-6055, 2018
662018
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
S Sainas, AC Pippione, M Giorgis, E Lupino, P Goyal, C Ramondetti, ...
European Journal of Medicinal Chemistry 129, 287-302, 2017
582017
Secretion and functional display of fusion proteins through the curli biogenesis pathway
N Van Gerven, P Goyal, G Vandenbussche, M De Kerpel, W Jonckheere, ...
Molecular microbiology 91 (5), 1022-1035, 2014
552014
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid
AC Pippione, IM Carnovale, D Bonanni, M Sini, P Goyal, E Marini, K Pors, ...
European Journal of Medicinal Chemistry 150, 930-945, 2018
492018
“Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes
RA North, CR Horne, JS Davies, DM Remus, AC Muscroft-Taylor, P Goyal, ...
Biophysical Reviews 10, 219-227, 2018
382018
Bioisosteres of indomethacin as inhibitors of aldo-keto reductase 1C3
ML Lolli, IM Carnovale, AC Pippione, WY Wahlgren, D Bonanni, E Marini, ...
ACS medicinal chemistry letters 10 (4), 437-443, 2019
322019
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies
AC Pippione, S Sainas, P Goyal, I Fritzson, GC Cassiano, A Giraudo, ...
European journal of medicinal chemistry 163, 266-280, 2019
292019
Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids
P Maindola, R Raina, P Goyal, K Atmakuri, A Ojha, S Gupta, PJ Christie, ...
Nature communications 5 (1), 5322, 2014
292014
Crystallization and preliminary X-ray crystallographic analysis of the curli transporter CsgG
P Goyal, N Van Gerven, W Jonckheere, H Remaut
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
172013
Mechanistic insights into global suppressors of protein folding defects
G Chattopadhyay, J Bhowmick, K Manjunath, S Ahmed, P Goyal, ...
PLoS Genetics 18 (8), e1010334, 2022
132022
Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum
R Caing-Carlsson, P Goyal, A Sharma, S Ghosh, TG Setty, RA North, ...
Acta Crystallographica Section F: Structural Biology Communications 73 (6 …, 2017
112017
The mannose-specific lectin domains of Flo1p from Saccharomyces cerevisiae and Lg-Flo1p from S. pastorianus: crystallization and preliminary X-ray diffraction analysis of the …
FS Ielasi, P Goyal, M Sleutel, A Wohlkonig, RG Willaert
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
82013
Insights in peptide diffusion channels from the bacterial amyloid secretor CsgG
I Van den Broeck, P Goyal, H Remaut
Channels 9 (2), 65-67, 2015
72015
Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
P Goyal, KV Dhanabalan, M Scalise, R Friemann, C Indiveri, RCJ Dobson, ...
bioRxiv, 2024.03. 29.587382, 2024
2024
1C3 (AKR1C3)
ML Lolli, IM Carnovale, AC Pippione, WY Wahlgren, D Bonanni, E Marini, ...
2023
Mechanistic insights into global suppressors of protein folding defects (preprint)
G Chattopadhyay, J Bhowmick, K Manjunath, S Ahmed, P Goyal, ...
2021
Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
S Sainas, AC Pippione, E Lupino, M Giorgis, P Circosta, V Gaidano, ...
Journal of Medicinal Chemistry 62 (3), 1696-1696, 2019
2019
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors
S Sainas, AC Pippione, D Bonanni, M Giorgis, E Lupino, E Giraudo, ...
GIFC2018, 1-1, 2018
2018
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