| Nephron organoids derived from human pluripotent stem cells model kidney development and injury R Morizane, AQ Lam, BS Freedman, S Kishi, MT Valerius, JV Bonventre Nature biotechnology 33 (11), 1193-1200, 2015 | 792 | 2015 |
| Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids BS Freedman, CR Brooks, AQ Lam, H Fu, R Morizane, V Agrawal, ... Nature communications 6 (1), 8715, 2015 | 731 | 2015 |
| Flow-enhanced vascularization and maturation of kidney organoids in vitro KA Homan, N Gupta, KT Kroll, DB Kolesky, M Skylar-Scott, T Miyoshi, ... Nature methods 16 (3), 255-262, 2019 | 653 | 2019 |
| Prediction of DNA repair inhibitor response in short-term patient-derived ovarian cancer organoids SJ Hill, B Decker, EA Roberts, NS Horowitz, MG Muto, MJ Worley Jr, ... Cancer discovery 8 (11), 1404-1421, 2018 | 352 | 2018 |
| Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers AQ Lam, BS Freedman, R Morizane, PH Lerou, MT Valerius, ... Journal of the American Society of Nephrology 25 (6), 1211-1225, 2014 | 341 | 2014 |
| Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells R Morizane, JV Bonventre Nature protocols 12 (1), 195-207, 2017 | 191 | 2017 |
| Interleukin-1β activates a MYC-dependent metabolic switch in kidney stromal cells necessary for progressive tubulointerstitial fibrosis DR Lemos, M McMurdo, G Karaca, J Wilflingseder, IA Leaf, N Gupta, ... Journal of the American Society of Nephrology 29 (6), 1690-1705, 2018 | 169 | 2018 |
| Kidney organoids: a translational journey R Morizane, JV Bonventre Trends in molecular medicine 23 (3), 246-263, 2017 | 137 | 2017 |
| Differentiation of murine embryonic stem and induced pluripotent stem cells to renal lineage in vitro R Morizane, T Monkawa, H Itoh Biochemical and biophysical research communications 390 (4), 1334-1339, 2009 | 123 | 2009 |
| The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021 | 98 | 2021 |
| The role of microRNA-145 in human embryonic stem cell differentiation into vascular cells S Yamaguchi, K Yamahara, K Homma, S Suzuki, S Fujii, R Morizane, ... Atherosclerosis 219 (2), 468-474, 2011 | 87 | 2011 |
| Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses S Kishi, CR Brooks, K Taguchi, T Ichimura, Y Mori, A Akinfolarin, N Gupta, ... The Journal of clinical investigation 129 (11), 4797-4816, 2019 | 78 | 2019 |
| miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction R Morizane, S Fujii, T Monkawa, K Hiratsuka, S Yamaguchi, K Homma, ... Scientific reports 4 (1), 4578, 2014 | 72 | 2014 |
| Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair N Gupta, T Matsumoto, K Hiratsuka, E Garcia Saiz, C Zhang, P Galichon, ... Science translational medicine 14 (634), eabj4772, 2022 | 58 | 2022 |
| Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery K Hiratsuka, T Miyoshi, KT Kroll, NR Gupta, MT Valerius, T Ferrante, ... Science advances 8 (38), eabq0866, 2022 | 47 | 2022 |
| Kidney specific protein-positive cells derived from embryonic stem cells reproduce tubular structures in vitro and differentiate into renal tubular cells R Morizane, T Monkawa, S Fujii, S Yamaguchi, K Homma, Y Matsuzaki, ... PloS one 8 (6), e64843, 2013 | 47 | 2013 |
| Kidney organoids in translational medicine: disease modeling and regenerative medicine T Miyoshi, K Hiratsuka, EG Saiz, R Morizane Developmental Dynamics 249 (1), 34-45, 2020 | 46 | 2020 |
| Generation of kidney tubular organoids from human pluripotent stem cells S Yamaguchi, R Morizane, K Homma, T Monkawa, S Suzuki, S Fujii, ... Scientific reports 6 (1), 38353, 2016 | 44 | 2016 |
| Meclizine preconditioning protects the kidney against ischemia–reperfusion injury S Kishi, G Campanholle, VM Gohil, F Perocchi, CR Brooks, R Morizane, ... EBioMedicine 2 (9), 1090-1101, 2015 | 42 | 2015 |
| Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors K Hiratsuka, T Monkawa, T Akiyama, Y Nakatake, M Oda, SK Goparaju, ... Scientific reports 9 (1), 913, 2019 | 40 | 2019 |
Joseph BonventreProfessor of Medicine, HarvardVerified email at hms.harvard.edu
