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Ryuya Fukunaga
Ryuya Fukunaga
Associate Professor at Johns Hopkins University School of Medicine
Verified email at jhmi.edu - Homepage
Title
Cited by
Cited by
Year
Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode Nɛ-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification
T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ...
Chemistry & biology 15 (11), 1187-1197, 2008
4222008
Dicer partner proteins tune the length of mature miRNAs in flies and mammals
R Fukunaga, BW Han, JH Hung, J Xu, Z Weng, PD Zamore
Cell 151 (3), 533-546, 2012
2792012
The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer–editing conformation
M Tukalo, A Yaremchuk, R Fukunaga, S Yokoyama, S Cusack
Nature structural & molecular biology 12 (10), 923-930, 2005
2002005
Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease
ES Cenik, R Fukunaga, G Lu, R Dutcher, Y Wang, TMT Hall, PD Zamore
Molecular cell 42 (2), 172-184, 2011
1872011
dsRNA with 5′ overhangs contributes to endogenous and antiviral RNA silencing pathways in plants
R Fukunaga, JA Doudna
The EMBO journal 28 (5), 545-555, 2009
1662009
Crystallographic studies on multiple conformational states of active-site loops in pyrrolysyl-tRNA synthetase
T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ...
Journal of molecular biology 378 (3), 634-652, 2008
1272008
Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition
R Fukunaga, S Yokoyama
Nature structural & molecular biology 12 (10), 915-922, 2005
1262005
Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation
R Fukunaga, S Yokoyama
Journal of molecular biology 346 (1), 57-71, 2005
1142005
Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase
R Fukunaga, S Yokoyama
Journal of molecular biology 359 (4), 901-912, 2006
862006
Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus
M Kuratani, R Ishii, Y Bessho, R Fukunaga, T Sengoku, M Shirouzu, ...
Journal of Biological Chemistry 280 (16), 16002-16008, 2005
742005
Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization
M Naganuma, S Sekine, R Fukunaga, S Yokoyama
Proceedings of the National Academy of Sciences 106 (21), 8489-8494, 2009
662009
Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea
R Fukunaga, S Yokoyama
Nature structural & molecular biology 14 (4), 272-279, 2007
652007
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei
T Yanagisawa, R Ishii, R Fukunaga, O Nureki, S Yokoyama
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006
652006
Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production
SK Kandasamy, R Fukunaga
Proceedings of the National Academy of Sciences 113 (49), 14031-14036, 2016
632016
Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine
R Fukunaga, S Fukai, R Ishitani, O Nureki, S Yokoyama
Journal of Biological Chemistry 279 (9), 8396-8402, 2004
612004
Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain
R Fukunaga, S Yokoyama
Journal of Biological Chemistry 280 (33), 29937-29945, 2005
602005
Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase
HM Sasaki, S Sekine, T Sengoku, R Fukunaga, M Hattori, Y Utsunomiya, ...
Proceedings of the National Academy of Sciences 103 (40), 14744-14749, 2006
522006
Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA: Cys-tRNA synthase from Archaeoglobus fulgidus
R Fukunaga, S Yokoyama
Journal of molecular biology 370 (1), 128-141, 2007
502007
Inorganic phosphate blocks binding of pre‐mi RNA to Dicer‐2 via its PAZ domain
R Fukunaga, C Colpan, BW Han, PD Zamore
The EMBO journal 33 (4), 371-384, 2014
492014
Differences in microRNA-29 and pro-fibrotic gene expression in mouse and human hypertrophic cardiomyopathy
Y Liu, J Afzal, S Vakrou, GV Greenland, CC Talbot Jr, VB Hebl, Y Guan, ...
Frontiers in cardiovascular medicine 6, 170, 2019
442019
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