Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3 T Mäkinen, L Jussila, T Veikkola, T Karpanen, MI Kettunen, KJ Pulkkanen, ... Nature medicine 7 (2), 199-205, 2001 | 1052 | 2001 |
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy SE Day, MI Kettunen, FA Gallagher, DE Hu, M Lerche, J Wolber, ... Nature medicine 13 (11), 1382-1387, 2007 | 1035 | 2007 |
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate FA Gallagher, MI Kettunen, SE Day, DE Hu, JH Ardenkjær-Larsen, ... Nature 453 (7197), 940-943, 2008 | 958 | 2008 |
A model for gene therapy of human hereditary lymphedema MJ Karkkainen, A Saaristo, L Jussila, KA Karila, EC Lawrence, K Pajusola, ... Proceedings of the National Academy of Sciences 98 (22), 12677-12682, 2001 | 730 | 2001 |
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses TT Rissanen, JE Markkanen, M Gruchala, T Heikura, A Puranen, ... Circulation research 92 (10), 1098-1106, 2003 | 552 | 2003 |
Production of hyperpolarized [1, 4-13C2] malate from [1, 4-13C2] fumarate is a marker of cell necrosis and treatment response in tumors FA Gallagher, MI Kettunen, DE Hu, PR Jensen, M Karlsson, A Gisselsson, ... Proceedings of the National Academy of Sciences 106 (47), 19801-19806, 2009 | 377 | 2009 |
Magnetic resonance imaging of tumor glycolysis using hyperpolarized 13C-labeled glucose TB Rodrigues, EM Serrao, BWC Kennedy, DE Hu, MI Kettunen, ... Nature medicine 20 (1), 93-97, 2014 | 321 | 2014 |
Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy KM Brindle, SE Bohndiek, FA Gallagher, MI Kettunen Magnetic Resonance in Medicine 66 (2), 505-519, 2011 | 314 | 2011 |
Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration TT Rissanen, I Vajanto, MO Hiltunen, J Rutanen, MI Kettunen, M Niemi, ... The American journal of pathology 160 (4), 1393-1403, 2002 | 245 | 2002 |
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia GP Crossan, L van der Weyden, IV Rosado, F Langevin, PHL Gaillard, ... Nature genetics 43 (2), 147-152, 2011 | 243 | 2011 |
Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid: vitamin C as a probe for imaging redox status in vivo SE Bohndiek, MI Kettunen, D Hu, BWC Kennedy, J Boren, FA Gallagher, ... Journal of the American Chemical Society 133 (30), 11795-11801, 2011 | 218 | 2011 |
β-amyloid precursor protein transgenic mice that harbor diffuse Aβ deposits but do not form plaques show increased ischemic vulnerability: role of inflammation M Koistinaho, MI Kettunen, G Goldsteins, R Keinänen, A Salminen, M Ort, ... Proceedings of the National Academy of Sciences 99 (3), 1610-1615, 2002 | 213 | 2002 |
13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C‐labeled glutamine FA Gallagher, MI Kettunen, SE Day, M Lerche, KM Brindle Magnetic Resonance in Medicine: An Official Journal of the International …, 2008 | 203 | 2008 |
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator–activated receptor-γ2 isoform G Medina-Gomez, S Virtue, C Lelliott, R Boiani, M Campbell, ... Diabetes 54 (6), 1706-1716, 2005 | 199 | 2005 |
Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1‐13C] pyruvate and 13C magnetic resonance spectroscopic imaging SE Day, MI Kettunen, MK Cherukuri, JB Mitchell, MJ Lizak, HD Morris, ... Magnetic resonance in medicine 65 (2), 557-563, 2011 | 194 | 2011 |
Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model TT Rissanen, JE Markkanen, K Arve, J Rutanen, MI Kettunen, I Vajanto, ... The FASEB Journal 17 (1), 100-102, 2003 | 193 | 2003 |
Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after … MD Dunning, A Lakatos, L Loizou, M Kettunen, KM Brindle, RJM Franklin Journal of Neuroscience 24 (44), 9799-9810, 2004 | 185 | 2004 |
Effects of hematocrit and oxygen saturation level on blood spin‐lattice relaxation MJ Silvennoinen, MI Kettunen, RA Kauppinen Magnetic Resonance in Medicine: An Official Journal of the International …, 2003 | 176 | 2003 |
Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line A Utriainen, R Sormunen, M Kettunen, LS Carvalhaes, E Sajanti, L Eklund, ... Human molecular genetics 13 (18), 2089-2099, 2004 | 175 | 2004 |
Assignment of 1H Nuclear Magnetic Resonance Visible Polyunsaturated Fatty Acids in BT4C Gliomas Undergoing Ganciclovir-Thymidine Kinase Gene Therapy … JL Griffin, KK Lehtimäki, PK Valonen, OHJ Gröhn, MI Kettunen, ... Cancer Research 63 (12), 3195-3201, 2003 | 170 | 2003 |