Deep learning in cancer diagnosis, prognosis and treatment selection KA Tran, O Kondrashova, A Bradley, ED Williams, JV Pearson, N Waddell Genome Medicine 13, 1-17, 2021 | 368 | 2021 |
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian … O Kondrashova, M Nguyen, K Shield-Artin, AV Tinker, NNH Teng, ... Cancer discovery 7 (9), 984-998, 2017 | 359 | 2017 |
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma O Kondrashova, M Topp, K Nesic, E Lieschke, GY Ho, MI Harrell, ... Nature communications 9 (1), 3970, 2018 | 226 | 2018 |
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer E Sanij, KM Hannan, J Xuan, S Yan, JE Ahern, AS Trigos, N Brajanovski, ... Nature communications 11 (1), 2641, 2020 | 114 | 2020 |
Targeting DNA repair: the genome as a potential biomarker K Nesic, M Wakefield, O Kondrashova, CL Scott, IA McNeish The Journal of pathology 244 (5), 586-597, 2018 | 52 | 2018 |
Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma K Nesic, O Kondrashova, RM Hurley, CD McGehee, CJ Vandenberg, ... Cancer Research 81 (18), 4709-4722, 2021 | 48 | 2021 |
Verifying explainability of a deep learning tissue classifier trained on RNA-seq data M Yap, RL Johnston, H Foley, S MacDonald, O Kondrashova, KA Tran, ... Scientific reports 11 (1), 2641, 2021 | 45 | 2021 |
Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma J Creaney, AM Patch, V Addala, SA Sneddon, K Nones, IM Dick, YCG Lee, ... Genome Medicine 14 (1), 58, 2022 | 30 | 2022 |
An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice G Ellison, M Ahdesmäki, S Luke, PM Waring, A Wallace, R Wright, ... Human mutation 39 (3), 394-405, 2018 | 30 | 2018 |
CRISPR/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase H You, JU Mayer, RL Johnston, H Sivakumaran, S Ranasinghe, V Rivera, ... bioRxiv, 2020.07. 08.190694, 2020 | 28 | 2020 |
Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer VF Bonazzi, O Kondrashova, D Smith, K Nones, AT Sengal, R Ju, ... Genome Medicine 14, 1-19, 2022 | 26 | 2022 |
Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance RM Hurley, CD McGehee, K Nesic, C Correia, TM Weiskittel, RL Kelly, ... Nar Cancer 3 (3), zcab028, 2021 | 23 | 2021 |
Diverse mechanisms of PARP inhibitor resistance in ovarian cancer MJ Wakefield, K Nesic, O Kondrashova, CL Scott Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1872 (2), 188307, 2019 | 21 | 2019 |
Heritable defects in telomere and mitotic function selectively predispose to sarcomas ML Ballinger, S Pattnaik, PA Mundra, M Zaheed, E Rath, P Priestley, ... Science 379 (6629), 253-260, 2023 | 15 | 2023 |
Next batter up! Targeting cancers with KRAS-G12D mutations MN Zeissig, LM Ashwood, O Kondrashova, KD Sutherland Trends in Cancer, 2023 | 14 | 2023 |
BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus–associated T/NK-cell lymphoma N Sejic, LC George, RJ Tierney, C Chang, O Kondrashova, ... Blood Advances 4 (19), 4775-4787, 2020 | 14 | 2020 |
High-throughput amplicon-based copy number detection of 11 genes in formalin-fixed paraffin-embedded ovarian tumour samples by MLPA-seq O Kondrashova, CJ Love, S Lunke, AL Hsu, ... PLoS One 10 (11), e0143006, 2015 | 11* | 2015 |
Histone modifying enzymes in gynaecological cancers P Ramarao-Milne, O Kondrashova, S Barry, JD Hooper, JS Lee, ... Cancers 13 (4), 816, 2021 | 10 | 2021 |
Clarifying the role of EMSY in DNA repair in ovarian cancer O Kondrashova, CL Scott Cancer 125 (16), 2720-2724, 2019 | 10 | 2019 |
A mpli V ar: Mutation Detection in High‐Throughput Sequence from Amplicon‐Based Libraries AL Hsu, O Kondrashova, S Lunke, CJ Love, C Meldrum, ... Human Mutation 36 (4), 411-418, 2015 | 9 | 2015 |