Renwick CJ Dobson

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Juliet A. GerrardProfessor of Biochemistry, University of Auckland, New ZealandVerified email at auckland.ac.nz
Matthew A. PeruginiDepartment of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe UniversityVerified email at latrobe.edu.au
Geoffrey B JamesonProfessor in Structural Chemistry and Biology, Massey UniversityVerified email at massey.ac.nz
Grant PearceBiochemistry Lecturer, University of CanterburyVerified email at canterbury.ac.nz
André O. Hudson, Ph.D.Rochester Institute of TechnologyVerified email at rit.edu
Sarah C AtkinsonMonash University/RMIT UniversityVerified email at monash.edu
James M. MurphyHead of Inflammation Division, Walter and Eliza Hall Institute of Medical ResearchVerified email at wehi.edu.au
Craig HuttonSchool of Chemistry, University of MelbourneVerified email at unimelb.edu.au
Michael W. ParkerSt Vincent's Institute of Medical Research and The University of MelbourneVerified email at svi.edu.au
Rachel A NorthResearch Fellow, Department of Biochemistry and Biophysics, Stockholm UniversityVerified email at dbb.su.se
Sean DevenishPostdoc, University of CambridgeVerified email at cam.ac.uk
Jennifer CrowtherUniversity of EdinburghVerified email at ed.ac.uk
Andrew I. WebbThe Walter and Eliza Hall Institute of Medical Research,Verified email at wehi.edu.au
jeff babonwalter and eliza hall instituteVerified email at wehi.edu.au
John SilkeProfessor, The Walter and Eliza Hall InstituteVerified email at latrobe.edu.au
Joanne (Hulett) HildebrandPost Doctoral Scientist, WEHIVerified email at wehi.edu.au
Rosmarie FriemannResearcher, Sahlgrenska University Hospital, University of GothenburgVerified email at gu.se
Katherine A DonovanDana Farber Cancer Institute, Harvard Medical SchoolVerified email at crystal.harvard.edu
Nicos A NicolaDivision Head, Walter and Eliza Hall InstituteVerified email at wehi.edu.au
Jian-Guo ZhangSenior Research Scientist, The Walter and Eliza Hall Institute of Medical Research, MelbourneVerified email at wehi.edu.au

Renwick CJ Dobson

Professor of Chemical Biology, School of Biological Sciences, University of Canterbury

Verified email at canterbury.ac.nz - Homepage

Biochemistry Biomolecular Interactions Enzymes Enzyme Evolution Enzyme Engineering


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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016	6838	2016
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013	678	2013
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014	313	2014
The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad RCJ Dobson, K Valegård, JA Gerrard Journal of Molecular Biology 338 (2), 329-339, 2004	116	2004
Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5–7.5 D Mercadante, LD Melton, GE Norris, TS Loo, MAK Williams, RCJ Dobson, ... Biophysical Journal 103 (2), 303-312, 2012	98	2012
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ... Journal of Biological Chemistry 283 (41), 27598-27603, 2008	95	2008
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005	92	2005
Evolution of quaternary structure in a homotetrameric enzyme MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ... Journal of Molecular Biology 380 (4), 691-703, 2008	84	2008
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ... Biochemical Journal 411 (2), 351-360, 2008	79	2008
Structural and functional analysis of the GABARAP interaction motif (GIM) VV Rogov, A Stolz, AC Ravichandran, DO Rios‐Szwed, H Suzuki, A Kniss, ... EMBO reports 18 (8), 1382-1396, 2017	75	2017
Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism H Suzuki, K Tabata, E Morita, M Kawasaki, R Kato, RCJ Dobson, ... Structure 22 (1), 47-58, 2014	73	2014
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation K Chen, J Hu, DL Moore, R Liu, SA Kessans, K Breslin, IS Lucet, A Keniry, ... Proceedings of the National Academy of Sciences 112 (27), E3535-E3544, 2015	69	2015
Potential for bacteriophage endolysins to supplement or replace antibiotics in food production and clinical care MJ Love, D Bhandari, RCJ Dobson, C Billington Antibiotics 7 (1), 17, 2018	66	2018
Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis PJ Cross, RCJ Dobson, ML Patchett, EJ Parker Journal of Biological Chemistry 286 (12), 10216-10224, 2011	58	2011
Federated repositories of X-ray diffraction images S Androulakis, J Schmidberger, MA Bate, R DeGori, A Beitz, C Keong, ... Acta Crystallographica Section D: Biological Crystallography 64 (7), 810-814, 2008	56	2008
Molecular characterisation of a novel cassava associated circular ssDNA virus A Dayaram, A Opong, A Jäschke, J Hadfield, M Baschiera, RCJ Dobson, ... Virus research 166 (1), 130-135, 2012	55	2012
Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase RCJ Dobson, SRA Devenish, LA Turner, VR Clifford, FG Pearce, ... Biochemistry 44 (39), 13007-13013, 2005	53	2005
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard Biochimie 86 (4), 311-315, 2004	53	2004
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax JE Voss, SW Scally, NL Taylor, SC Atkinson, MDW Griffin, CA Hutton, ... Journal of Biological Chemistry 285 (8), 5188-5195, 2010	51	2010
The preparation of (S)-Aspartate semi-aldehyde appropriate for use in biochemical studies SJ Roberts, JC Morris, RCJ Dobson, JA Gerrard Bioorganic & medicinal chemistry letters 13 (2), 265-267, 2003	48	2003

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