Renwick CJ Dobson
Renwick CJ Dobson
Professor, School of Biological Sciences, University of Canterbury
Verified email at canterbury.ac.nz - Homepage
TitleCited byYear
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
23042016
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ...
Immunity 39 (3), 443-453, 2013
4882013
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
2172014
The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad
RCJ Dobson, K Valegård, JA Gerrard
Journal of Molecular Biology 338 (2), 329-339, 2004
1082004
Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen
BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ...
Journal of Biological Chemistry 283 (41), 27598-27603, 2008
892008
The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance
RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard
Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005
892005
Evolution of quaternary structure in a homotetrameric enzyme
MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ...
Journal of Molecular Biology 380 (4), 691-703, 2008
812008
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis
G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ...
Biochemical Journal 411 (2), 351-360, 2008
762008
Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5–7.5
D Mercadante, LD Melton, GE Norris, TS Loo, MAK Williams, RCJ Dobson, ...
Biophysical Journal 103 (2), 303-312, 2012
742012
Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism
H Suzuki, K Tabata, E Morita, M Kawasaki, R Kato, RCJ Dobson, ...
Structure 22 (1), 47-58, 2014
562014
Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase
RCJ Dobson, SRA Devenish, LA Turner, VR Clifford, FG Pearce, ...
Biochemistry 44 (39), 13007-13013, 2005
522005
Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
PJ Cross, RCJ Dobson, ML Patchett, EJ Parker
Journal of Biological Chemistry 286 (12), 10216-10224, 2011
512011
Federated repositories of X-ray diffraction images
S Androulakis, J Schmidberger, MA Bate, R DeGori, A Beitz, C Keong, ...
Acta Crystallographica Section D: Biological Crystallography 64 (7), 810-814, 2008
512008
Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate
RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard
Biochimie 86 (4), 311-315, 2004
482004
Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax
JE Voss, SW Scally, NL Taylor, SC Atkinson, MDW Griffin, CA Hutton, ...
Journal of Biological Chemistry 285 (8), 5188-5195, 2010
472010
The preparation of (S)-Aspartate semi-aldehyde appropriate for use in biochemical studies
SJ Roberts, JC Morris, RCJ Dobson, JA Gerrard
Bioorganic & medicinal chemistry letters 13 (2), 265-267, 2003
472003
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation
K Chen, J Hu, DL Moore, R Liu, SA Kessans, K Breslin, IS Lucet, A Keniry, ...
Proceedings of the National Academy of Sciences 112 (27), E3535-E3544, 2015
462015
Molecular characterisation of a novel cassava associated circular ssDNA virus
A Dayaram, A Opong, A Jäschke, J Hadfield, M Baschiera, RCJ Dobson, ...
Virus research 166 (1), 130-135, 2012
452012
Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde
RCJ Dobson, JA Gerrard, FG Pearce
Biochemical Journal 377 (3), 757-762, 2004
442004
Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?
V Mitsakos, RCJ Dobson, FG Pearce, SR Devenish, GL Evans, ...
Bioorganic & medicinal chemistry letters 18 (2), 842-844, 2008
422008
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