| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 5970 | 2016 |
| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 577 | 2013 |
| Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014 | 266 | 2014 |
| The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad RCJ Dobson, K Valegård, JA Gerrard Journal of Molecular Biology 338 (2), 329-339, 2004 | 107 | 2004 |
| Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ... Journal of Biological Chemistry 283 (41), 27598-27603, 2008 | 95 | 2008 |
| The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005 | 92 | 2005 |
| Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5–7.5 D Mercadante, LD Melton, GE Norris, TS Loo, MAK Williams, RCJ Dobson, ... Biophysical Journal 103 (2), 303-312, 2012 | 85 | 2012 |
| Evolution of quaternary structure in a homotetrameric enzyme MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ... Journal of Molecular Biology 380 (4), 691-703, 2008 | 80 | 2008 |
| Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ... Biochemical Journal 411 (2), 351-360, 2008 | 79 | 2008 |
| Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism H Suzuki, K Tabata, E Morita, M Kawasaki, R Kato, RCJ Dobson, ... Structure 22 (1), 47-58, 2014 | 65 | 2014 |
| Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation K Chen, J Hu, DL Moore, R Liu, SA Kessans, K Breslin, IS Lucet, A Keniry, ... Proceedings of the National Academy of Sciences 112 (27), E3535-E3544, 2015 | 57 | 2015 |
| Structural and functional analysis of the GABARAP interaction motif (GIM) VV Rogov, A Stolz, AC Ravichandran, DO Rios‐Szwed, H Suzuki, A Kniss, ... EMBO reports 18 (8), 1382-1396, 2017 | 55 | 2017 |
| Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard Biochimie 86 (4), 311-315, 2004 | 54 | 2004 |
| Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis PJ Cross, RCJ Dobson, ML Patchett, EJ Parker Journal of Biological Chemistry 286 (12), 10216-10224, 2011 | 53 | 2011 |
| Federated repositories of X-ray diffraction images S Androulakis, J Schmidberger, MA Bate, R DeGori, A Beitz, C Keong, ... Acta Crystallographica Section D: Biological Crystallography 64 (7), 810-814, 2008 | 53 | 2008 |
| Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase RCJ Dobson, SRA Devenish, LA Turner, VR Clifford, FG Pearce, ... Biochemistry 44 (39), 13007-13013, 2005 | 53 | 2005 |
| Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax JE Voss, SW Scally, NL Taylor, SC Atkinson, MDW Griffin, CA Hutton, ... Journal of Biological Chemistry 285 (8), 5188-5195, 2010 | 50 | 2010 |
| Molecular characterisation of a novel cassava associated circular ssDNA virus A Dayaram, A Opong, A Jäschke, J Hadfield, M Baschiera, RCJ Dobson, ... Virus research 166 (1), 130-135, 2012 | 49 | 2012 |
| The preparation of (S)-Aspartate semi-aldehyde appropriate for use in biochemical studies SJ Roberts, JC Morris, RCJ Dobson, JA Gerrard Bioorganic & medicinal chemistry letters 13 (2), 265-267, 2003 | 47 | 2003 |
| Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain PJ Cross, TM Allison, RCJ Dobson, GB Jameson, EJ Parker Proceedings of the National Academy of Sciences 110 (6), 2111-2116, 2013 | 44 | 2013 |
Juliet A. GerrardProfessor of Biochemistry, University of Auckland, New ZealandVerified email at auckland.ac.nz
