| Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress K Zaugg, Y Yao, PT Reilly, K Kannan, R Kiarash, J Mason, P Huang, ... Genes & development 25 (10), 1041-1051, 2011 | 516 | 2011 |
| TAp73 knockout shows genomic instability with infertility and tumor suppressor functions R Tomasini, K Tsuchihara, M Wilhelm, M Fujitani, A Rufini, CC Cheung, ... Genes & development 22 (19), 2677-2691, 2008 | 513 | 2008 |
| FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal H You, M Pellegrini, K Tsuchihara, K Yamamoto, G Hacker, M Erlacher, ... The Journal of experimental medicine 203 (7), 1657-1663, 2006 | 496 | 2006 |
| Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation K Sato, K Tsuchihara, S Fujii, M Sugiyama, T Goya, Y Atomi, T Ueno, ... Cancer research 67 (20), 9677-9684, 2007 | 419 | 2007 |
| Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial K Yoh, T Seto, M Satouchi, M Nishio, N Yamamoto, H Murakami, ... The Lancet Respiratory Medicine 5 (1), 42-50, 2017 | 309 | 2017 |
| Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer T Kohno, T Nakaoku, K Tsuta, K Tsuchihara, S Matsumoto, K Yoh, K Goto Translational lung cancer research 4 (2), 156, 2015 | 278 | 2015 |
| Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies Y Nakamura, H Taniguchi, M Ikeda, H Bando, K Kato, C Morizane, T Esaki, ... Nature medicine 26 (12), 1859-1864, 2020 | 264 | 2020 |
| Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway MT Wilhelm, A Rufini, MK Wetzel, K Tsuchihara, S Inoue, R Tomasini, ... Genes & development 24 (6), 549-560, 2010 | 258 | 2010 |
| ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress W Assaily, DA Rubinger, K Wheaton, Y Lin, W Ma, W Xuan, ... Molecular cell 44 (3), 491-501, 2011 | 195 | 2011 |
| Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma H Makinoshima, M Takita, S Matsumoto, A Yagishita, S Owada, H Esumi, ... Journal of Biological Chemistry 289 (30), 20813-20823, 2014 | 194 | 2014 |
| Signaling through the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) axis is responsible for aerobic glycolysis mediated by glucose transporter in … H Makinoshima, M Takita, K Saruwatari, S Umemura, Y Obata, G Ishii, ... Journal of Biological Chemistry 290 (28), 17495-17504, 2015 | 186 | 2015 |
| Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis S Umemura, S Mimaki, H Makinoshima, S Tada, G Ishii, H Ohmatsu, ... Journal of Thoracic Oncology 9 (9), 1324-1331, 2014 | 184 | 2014 |
| Genomic profiling of large-cell neuroendocrine carcinoma of the lung T Miyoshi, S Umemura, Y Matsumura, S Mimaki, S Tada, H Makinoshima, ... Clinical Cancer Research 23 (3), 757-765, 2017 | 179 | 2017 |
| Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues K Tsuchihara, S Fujii, H Esumi Cancer letters 278 (2), 130-138, 2009 | 171 | 2009 |
| TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity R Tomasini, K Tsuchihara, C Tsuda, SK Lau, M Wilhelm, A Rufini, M Tsao, ... Proceedings of the National Academy of Sciences 106 (3), 797-802, 2009 | 162 | 2009 |
| Specific interaction of polypyrimidine tract-binding protein with the extreme 3'-terminal structure of the hepatitis C virus genome, the 3'X K Tsuchihara, T Tanaka, M Hijikata, S Kuge, H Toyoda, A Nomoto, ... Journal of Virology 71 (9), 6720-6726, 1997 | 158 | 1997 |
| Hepatitis C virus core protein regulates cell growth and signal transduction pathway transmitting growth stimuli K Tsuchihara, M Hijikata, K Fukuda, T Kuroki, N Yamamoto, ... Virology 258 (1), 100-107, 1999 | 149 | 1999 |
| Amplification of EGFR wild-type alleles in non–small cell lung cancer cells confers acquired resistance to mutation-selective EGFR tyrosine kinase inhibitors S Nukaga, H Yasuda, K Tsuchihara, J Hamamoto, K Masuzawa, I Kawada, ... Cancer research 77 (8), 2078-2089, 2017 | 144 | 2017 |
| RET fusion gene: Translation to personalized lung cancer therapy T Kohno, K Tsuta, K Tsuchihara, T Nakaoku, K Yoh, K Goto Cancer science 104 (11), 1396-1400, 2013 | 136 | 2013 |
| Massive transcriptional start site analysis of human genes in hypoxia cells K Tsuchihara, Y Suzuki, H Wakaguri, T Irie, K Tanimoto, S Hashimoto, ... Nucleic acids research 37 (7), 2249-2263, 2009 | 132 | 2009 |
Takashi KohnoNational Cancer CenterVerified email at ncc.go.jp
