Emmanuel Margolin
Emmanuel Margolin
Institute of Infectious Diseases and Molecular Medicine, University of Cape Town
Verified email at
Cited by
Cited by
Production of complex viral glycoproteins in plants as vaccine immunogens
E Margolin, R Chapman, AL Williamson, EP Rybicki, AE Meyers
Plant biotechnology journal 16 (9), 1531-1545, 2018
Co‐expression of human calreticulin significantly improves the production of HIV gp140 and other viral glycoproteins in plants
E Margolin, YJ Oh, M Verbeek, J Naude, D Ponndorf, YA Meshcheriakova, ...
Plant Biotechnology Journal 18 (10), 2109-2117, 2020
Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa
E Margolin, WA Burgers, ED Sturrock, M Mendelson, R Chapman, ...
Nature Reviews Microbiology 18 (12), 690-704, 2020
N-glycosylation of the SARS-CoV-2 receptor binding domain is important for functional expression in plants
YJ Shin, J König-Beihammer, U Vavra, J Schwestka, NF Kienzl, ...
Frontiers in Plant Science 12, 689104, 2021
Engineering the plant secretory pathway for the production of next-generation pharmaceuticals
EA Margolin, R Strasser, R Chapman, AL Williamson, EP Rybicki, ...
Trends in Biotechnology 38 (9), 1034-1044, 2020
Production and immunogenicity of soluble plant-produced HIV-1 subtype C envelope gp140 immunogens
E Margolin, R Chapman, AE Meyers, MT Van Diepen, P Ximba, ...
Frontiers in plant science 10, 1378, 2019
Prime-boost immunizations with DNA, modified vaccinia virus Ankara, and protein-based vaccines elicit robust HIV-1 tier 2 neutralizing antibodies against the CAP256 …
MT van Diepen, R Chapman, N Douglass, S Galant, PL Moore, ...
Journal of virology 93 (8), 10.1128/jvi. 02155-18, 2019
A roadmap for the molecular farming of viral glycoprotein vaccines: engineering glycosylation and glycosylation-directed folding
E Margolin, M Crispin, A Meyers, R Chapman, EP Rybicki
Frontiers in Plant Science 11, 609207, 2020
The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256
MT van Diepen, R Chapman, PL Moore, E Margolin, T Hermanus, ...
PLoS One 13 (12), e0208310, 2018
Site-Specific Glycosylation of Recombinant Viral Glycoproteins Produced in Nicotiana benthamiana
E Margolin, JD Allen, M Verbeek, M Van Diepen, P Ximba, R Chapman, ...
Frontiers in Plant Science 12, 709344, 2021
Immunogenicity of HIV-1 vaccines expressing chimeric envelope glycoproteins on the surface of Pr55 Gag virus-like particles
R Chapman, M van Diepen, S Galant, E Kruse, E Margolin, P Ximba, ...
Vaccines 8 (1), 54, 2020
A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters
E Margolin, G Schäfer, JD Allen, S Gers, J Woodward, AD Sutherland, ...
Frontiers in Plant Science 14, 1146234, 2023
Investigating constraints along the plant secretory pathway to improve production of a SARS-CoV-2 spike vaccine candidate
E Margolin, M Verbeek, W de Moor, R Chapman, A Meyers, G Schäfer, ...
Frontiers in Plant Science 12, 798822, 2022
Calreticulin co-expression supports high level production of a recombinant SARS-CoV-2 spike mimetic in Nicotiana benthamiana
E Margolin, M Verbeek, A Meyers, R Chapman, AL Williamson, ...
BioRxiv, 2020.06. 14.150458, 2020
Assessment of an LSDV-vectored vaccine for heterologous prime-boost immunizations against HIV
R Chapman, M van Diepen, N Douglass, S Galant, M Jaffer, E Margolin, ...
Vaccines 9 (11), 1281, 2021
Augmenting glycosylation‐directed folding pathways enhances the fidelity of HIV Env immunogen production in plants
E Margolin, JD Allen, M Verbeek, R Chapman, A Meyers, M van Diepen, ...
Biotechnology and Bioengineering 119 (10), 2919-2937, 2022
Development of a synthetic nanoparticle vaccine presenting the HIV-1 envelope glycoprotein
P Ximba, R Chapman, A Meyers, E Margolin, MT van Diepen, AF Sander, ...
Nanotechnology 33 (48), 485102, 2022
Characterization and Immunogenicity of HIV Envelope gp140 Zera® Tagged Antigens
P Ximba, R Chapman, AE Meyers, E Margolin, MT Van Diepen, ...
Frontiers in Bioengineering and Biotechnology 8, 321, 2020
Development of a dual vaccine against East Coast fever and lumpy skin disease
L Whittle, R Chapman, N Douglass, M Jaffer, E Margolin, E Rybicki, ...
Frontiers in Immunology 14, 1143034, 2023
Co-expression of human chaperone proteins in plants for increased expression of heterologous polypeptides
AE Meyers, EP Rybicki, EA Margolin
US Patent 11,555,196, 2023
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