Production of complex viral glycoproteins in plants as vaccine immunogens E Margolin, R Chapman, AL Williamson, EP Rybicki, AE Meyers Plant biotechnology journal 16 (9), 1531-1545, 2018 | 81 | 2018 |
Co‐expression of human calreticulin significantly improves the production of HIV gp140 and other viral glycoproteins in plants E Margolin, YJ Oh, M Verbeek, J Naude, D Ponndorf, YA Meshcheriakova, ... Plant Biotechnology Journal 18 (10), 2109-2117, 2020 | 66 | 2020 |
Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa E Margolin, WA Burgers, ED Sturrock, M Mendelson, R Chapman, ... Nature Reviews Microbiology 18 (12), 690-704, 2020 | 64 | 2020 |
N-glycosylation of the SARS-CoV-2 receptor binding domain is important for functional expression in plants YJ Shin, J König-Beihammer, U Vavra, J Schwestka, NF Kienzl, ... Frontiers in Plant Science 12, 689104, 2021 | 60 | 2021 |
Engineering the plant secretory pathway for the production of next-generation pharmaceuticals EA Margolin, R Strasser, R Chapman, AL Williamson, EP Rybicki, ... Trends in Biotechnology 38 (9), 1034-1044, 2020 | 54 | 2020 |
Production and immunogenicity of soluble plant-produced HIV-1 subtype C envelope gp140 immunogens E Margolin, R Chapman, AE Meyers, MT Van Diepen, P Ximba, ... Frontiers in plant science 10, 1378, 2019 | 43 | 2019 |
Prime-boost immunizations with DNA, modified vaccinia virus Ankara, and protein-based vaccines elicit robust HIV-1 tier 2 neutralizing antibodies against the CAP256 … MT van Diepen, R Chapman, N Douglass, S Galant, PL Moore, ... Journal of virology 93 (8), 10.1128/jvi. 02155-18, 2019 | 38 | 2019 |
A roadmap for the molecular farming of viral glycoprotein vaccines: engineering glycosylation and glycosylation-directed folding E Margolin, M Crispin, A Meyers, R Chapman, EP Rybicki Frontiers in Plant Science 11, 609207, 2020 | 29 | 2020 |
The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256 MT van Diepen, R Chapman, PL Moore, E Margolin, T Hermanus, ... PLoS One 13 (12), e0208310, 2018 | 20 | 2018 |
Immunogenicity of HIV-1 vaccines expressing chimeric envelope glycoproteins on the surface of Pr55 Gag virus-like particles R Chapman, M van Diepen, S Galant, E Kruse, E Margolin, P Ximba, ... Vaccines 8 (1), 54, 2020 | 17 | 2020 |
A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters E Margolin, G Schäfer, JD Allen, S Gers, J Woodward, AD Sutherland, ... Frontiers in Plant Science 14, 1146234, 2023 | 16 | 2023 |
Site-Specific Glycosylation of Recombinant Viral Glycoproteins Produced in Nicotiana benthamiana E Margolin, JD Allen, M Verbeek, M Van Diepen, P Ximba, R Chapman, ... Frontiers in Plant Science 12, 709344, 2021 | 16 | 2021 |
Investigating constraints along the plant secretory pathway to improve production of a SARS-CoV-2 spike vaccine candidate E Margolin, M Verbeek, W de Moor, R Chapman, A Meyers, G Schäfer, ... Frontiers in Plant Science 12, 798822, 2022 | 13 | 2022 |
Calreticulin co-expression supports high level production of a recombinant SARS-CoV-2 spike mimetic in Nicotiana benthamiana E Margolin, M Verbeek, A Meyers, R Chapman, AL Williamson, ... BioRxiv, 2020.06. 14.150458, 2020 | 13 | 2020 |
Augmenting glycosylation‐directed folding pathways enhances the fidelity of HIV Env immunogen production in plants E Margolin, JD Allen, M Verbeek, R Chapman, A Meyers, M van Diepen, ... Biotechnology and Bioengineering 119 (10), 2919-2937, 2022 | 7 | 2022 |
Development of a synthetic nanoparticle vaccine presenting the HIV-1 envelope glycoprotein P Ximba, R Chapman, A Meyers, E Margolin, MT van Diepen, AF Sander, ... Nanotechnology 33 (48), 485102, 2022 | 6 | 2022 |
Assessment of an LSDV-vectored vaccine for heterologous prime-boost immunizations against HIV R Chapman, M van Diepen, N Douglass, S Galant, M Jaffer, E Margolin, ... Vaccines 9 (11), 1281, 2021 | 6 | 2021 |
Development of a dual vaccine against East Coast fever and lumpy skin disease L Whittle, R Chapman, N Douglass, M Jaffer, E Margolin, E Rybicki, ... Frontiers in Immunology 14, 1143034, 2023 | 5 | 2023 |
Characterization and Immunogenicity of HIV Envelope gp140 Zera® Tagged Antigens P Ximba, R Chapman, AE Meyers, E Margolin, MT Van Diepen, ... Frontiers in Bioengineering and Biotechnology 8, 321, 2020 | 5 | 2020 |
LSDV-Vectored SARS-CoV-2 S and N vaccine protects against severe clinical disease in hamsters WRJ de Moor, AL Williamson, G Schäfer, N Douglass, S Gers, ... Viruses 15 (7), 1409, 2023 | 2 | 2023 |