Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models ML Cook Sangar, LA Genovesi, MW Nakamoto, MJ Davis, SE Knobluagh, ... Clinical Cancer Research 23 (19), 5802-5813, 2017 | 97 | 2017 |
Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations L Harris, LA Genovesi, RM Gronostajski, BJ Wainwright, M Piper Developmental dynamics 244 (3), 227-238, 2015 | 79 | 2015 |
Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups LA Genovesi, CG Ng, MJ Davis, M Remke, MD Taylor, DJ Adams, ... Proceedings of the National Academy of Sciences 110 (46), E4325-E4334, 2013 | 73 | 2013 |
Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cells LA Genovesi, KW Carter, NG Gottardo, KM Giles, PB Dallas PloS one 6 (9), e23935, 2011 | 52 | 2011 |
Elongator mutation in mice induces neurodegeneration and ataxia-like behavior M Kojic, M Gaik, B Kiska, A Salerno-Kochan, S Hunt, A Tedoldi, S Mureev, ... Nature communications 9 (1), 3195, 2018 | 48 | 2018 |
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype M Kojic, T Gawda, M Gaik, A Begg, A Salerno-Kochan, ND Kurniawan, ... Nature communications 12 (1), 2678, 2021 | 36 | 2021 |
Comparative study of preclinical mouse models of high-grade glioma for nanomedicine research: the importance of reproducing blood-brain barrier heterogeneity C Brighi, L Reid, LA Genovesi, M Kojic, A Millar, Z Bruce, AL White, ... Theranostics 10 (14), 6361, 2020 | 36 | 2020 |
Identification of suitable endogenous control genes for microRNA expression profiling of childhood medulloblastoma and human neural stem cells LA Genovesi, D Anderson, KW Carter, KM Giles, PB Dallas BMC research notes 5, 1-12, 2012 | 28 | 2012 |
Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility C Adolphe, A Xue, AT Fard, LA Genovesi, J Yang, BJ Wainwright Genome Medicine 13, 1-12, 2021 | 26 | 2021 |
MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma C Brighi, L Reid, AL White, LA Genovesi, M Kojic, A Millar, Z Bruce, ... Neuro-Oncology Advances 2 (1), vdaa030, 2020 | 23 | 2020 |
Patient-derived orthotopic xenograft models of medulloblastoma lack a functional blood-brain barrier LA Genovesi, S Puttick, A Millar, M Kojic, P Ji, AK Lagendijk, C Brighi, ... Neuro-oncology 23 (5), 732-742, 2021 | 14 | 2021 |
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma LA Genovesi, A Millar, E Tolson, M Singleton, E Hassall, M Kojic, C Brighi, ... Genome Medicine 13 (1), 103, 2021 | 11 | 2021 |
Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models EK Morris, S Daignault-Mill, SJ Stehbens, LA Genovesi, AK Lagendijk Frontiers in oncology 13, 1101522, 2023 | 7 | 2023 |
Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 … T Vo, B Balderson, K Jones, G Ni, J Crawford, A Millar, E Tolson, ... Genome Medicine 15 (1), 29, 2023 | 6 | 2023 |
SOX9 defines distinct populations of cells in SHH medulloblastoma but is not required for math1-driven tumor formation C Adolphe, A Millar, M Kojic, DS Barkauskas, A Sundström, FJ Swartling, ... Molecular Cancer Research 19 (11), 1831-1839, 2021 | 6 | 2021 |
Applying spatial omics and computational integrative analyses to study drug responses and cancer immune cell interactions X Tan, A Causer, TQA Vo, N Ma, BB Cheikh, L Genovesi, ... Cancer Research 83 (7_Supplement), 4703-4703, 2023 | 1 | 2023 |
NEURO-ONCOLOGY FM MBL Neuro-Oncology 16, i71-i96, 2014 | 1 | 2014 |
MDB-42. UNCOVERING DYNAMIC CHANGES IN MEDULLOBLASTOMA ASSOCIATED VASCULATURE IN ZEBRAFISH E Morris, S Daignault-Mill, RJ Ju, J da Silva, E Gordon, B Wainwright, ... Neuro-Oncology 25 (Suppl 1), i71, 2023 | | 2023 |
SPATIAL TRANSCRIPTOMIC ANALYSIS OF SONIC HEDGEHOG MEDULLOBLASTOMA IDENTIFIES THAT LOSS OF HETEROGENEITY AND INDUCED DIFFERENTIATION UNDERLIES THE RESPONSE TO CDK4/6 INHIBITION T Vo, B Balderson, K Jones, J Crawford, A Millar, E Tolson, M Ruitenberg, ... NEURO-ONCOLOGY 24, 105-105, 2022 | | 2022 |
MEDB-06. SPATIAL TRANSCRIPTOMIC ANALYSIS OF SONIC HEDGEHOG MEDULLOBLASTOMA IDENTIFIES THAT LOSS OF HETEROGENEITY AND INDUCED DIFFERENTIATION UNDERLIES THE RESPONSE TO CDK4/6 … Z Spinello, L Abballe, E Splendiani, A Di Giannatale, F Giangaspero, ... Neuro-oncology, 2022 | | 2022 |